Service Centre category(ies)
Spectrometry / Crystallography
Description of the Service Centre
Solid state chemistry in its broadest manifestation involves using the crystal structure and solid state analytical information to explain solid-state properties, which is crucial to develop new drugs. At Hovione, the mission of the group is to collaborate with customers in the field of solid state, particularly in the characterization of solid phases of raw materials to finished products, from API to drug products in all stages of development and production. Innovation is continuously promoted.
Service Centre web address
Contact person's name
Constança Cacela
Contact person's e-mail
ccacela @hovione.com
Contact person's telephone
+351 219 829 359
Service
Solid State Characterization - Chemistry
Available for external use?
No
Comments
1) Characterization and stability of polymorphs; 2) Phase transformations; 3) Characterization of Solvates and hydrates. 4) Screening and selection of polymorphs.
Service
Solid State Characterization - Particle design
Available for external use?
No
Comments
Amorphous forms and solid dispersions: screening, stability and selection; glass transition temperatures; relaxation studies.
Service
Particle Characterization
Available for external use?
No
Comments
Morphology, particle size determination, fine tune of particle size, stabilization of nanoparticles.
Service
Methods development and validation
Available for external use?
No
Comments
1 Detection and quantitation of solid phases in API, drug products, tablets and capsules. 2 Problem solving and development studies. 3 Methods (DSC, TGA, PSD, XRPD): transfers, qualifications, reduced and full validations.
Equipment
X-Ray Powder Diffractometer (XRPD), X´Pert Pro, PANalytical
Service type: self-service or full-service?
Full-service
Equipment
Differential Scanning Calorimeter (DSC), Q200, TA instruments
Service type: self-service or full-service?
Full-service
Equipment
Thermal Gravimetric Analyser (TGA), Q500, TA instruments
Service type: self-service or full-service?
Full-service
Equipment
Fourier Transform Infrared Spectroscopy (FTIR), Avatar 360, Nicolet
Service type: self-service or full-service?
Full-service
Equipment
Microscope, BA310 Series, Motic
Service type: self-service or full-service?
Full-service
Comments
Microscope with polarizer and camera (Moticam 2500, Motic)
Equipment
Other in-house available techniques: NIR, DVS and hot stage microscopy
Service type: self-service or full-service?
Full-service