All Institutions
Search all resources
Search for entire words only

BIA 5 - 1058

BIAL - Portela & Cª, S.A.
Project classification

Scientific area

3.1 Basic medicine


Pharmacology and pharmacy

Project description

Project title

BIA 5 - 1058

Scientific Coordinator's name:

Prof. Patrício Soares-da-Silva

Scientific Coordinator's e-mail:

Principal R&D Unit:

Prof. Patrício Soares-da-Silva

Other R&D Units involved in the project:

Other R&D units involved in the project

Project keyword(s)

BIA 5-1058, Cardiovascular Diseases, dopamine ß-hydroxylase

Short abstract and comments

BIA 5-1058 is currently under developed by BIAL - Portela & Cª, S.A. for the treatment of cardiovascular diseases. BIA 5-1058 is a reversible dopamine ß-hydroxylase (DßH) inhibitor that prevents the conversion of dopamine (DA) to norepinephrine (NE) in sympathetically innervated tissues and slows down the drive of sympathetic nervous system. BIA 5-1058 is a peripherally-selective inhibitor the selectivity of which is associated with its reduced ability to cross the blood-brain barrier.

Potential uses/indications

Cardiovascular Diseases



Partner Status: Seeking Partners?


Grant number (QREN, FP7, Eureka, etc)


Last edited on

2011-11-09 14:38:26

Health Cluster Portugal All rights reserved
© 2024 Health Cluster Portugal All rights reserved