Scientific area
3.1 Basic medicine
Discipline(s)
Pharmacology and pharmacy
Project title
BIA 5 - 1058
Scientific Coordinator's name:
Prof. Patrício Soares-da-Silva
Scientific Coordinator's e-mail:
psoares.silva@bial.com
Principal R&D Unit:
Prof. Patrício Soares-da-Silva
Other R&D Units involved in the project:
Other R&D units involved in the project
Project keyword(s)
BIA 5-1058, Cardiovascular Diseases, dopamine ß-hydroxylase
Short abstract and comments
BIA 5-1058 is currently under developed by BIAL - Portela & Cª, S.A. for the treatment of cardiovascular diseases. BIA 5-1058 is a reversible dopamine ß-hydroxylase (DßH) inhibitor that prevents the conversion of dopamine (DA) to norepinephrine (NE) in sympathetically innervated tissues and slows down the drive of sympathetic nervous system. BIA 5-1058 is a peripherally-selective inhibitor the selectivity of which is associated with its reduced ability to cross the blood-brain barrier.
Potential uses/indications
Cardiovascular Diseases
Status
Ongoing
Partner Status: Seeking Partners?
Yes
Grant number (QREN, FP7, Eureka, etc)
QREN 27
Last edited on
2011-11-09 14:38:26