Services Centres
3D Printing and Prototyping -
INEGI - Institute of Science and Innovation in Mechanical and Industrial Engineering
This service centre provides for the manufacturing of body-shaped parts/prototypes for biomechanical applications, such as anatomical models, orthotic devices and/or sports equipment.
This service centre provides for the manufacturing of body-shaped parts/prototypes for biomechanical applications, such as anatomical models, orthotic devices and/or sports equipment.
4C – Coimbra Coordinating Centre for Clinical Research -
AIBILI - Association for Innovation and Biomedical Research on Light and Image
The Coimbra Coordinating Centre for Clinical Research 4C is a structure to support Investigator-Initiated and Industry-Sponsored Clinical Research complying with ICH GCP - Good Clinical Practice Guidelines and European regulations, namely Clinical Trials Regulation (Regulation (EU) No 536/2014), Medical Devices Regulation (Regulation (EU) No 2017/745) and ISO 14155. 4C provides the necessary logistical support to perform multinational clinical research in Europe.
The Coimbra Coordinating Centre for Clinical Research 4C is a structure to support Investigator-Initiated and Industry-Sponsored Clinical Research complying with ICH GCP - Good Clinical Practice Guidelines and European regulations, namely Clinical Trials Regulation (Regulation (EU) No 536/2014), Medical Devices Regulation (Regulation (EU) No 2017/745) and ISO 14155. 4C provides the necessary logistical support to perform multinational clinical research in Europe.
Advanced Flow Cytometry Unit -
IBMC - Institute for Molecular and Cell Biology
The AFCU provides investigators with equipment for acquisition and analysis of flow cytometric data and for cell sorting from single cell suspension using fluorescence. Furthermore, the AFCU gives training and consulting for researchers that intend to use flow cytometry in their projects; and helps analyzing and interpreting data. A number of applications, including the multicolour analysis of cell phenotype, gene expression, membrane potential, cell cycle, among others, can be performed.
The AFCU provides investigators with equipment for acquisition and analysis of flow cytometric data and for cell sorting from single cell suspension using fluorescence. Furthermore, the AFCU gives training and consulting for researchers that intend to use flow cytometry in their projects; and helps analyzing and interpreting data. A number of applications, including the multicolour analysis of cell phenotype, gene expression, membrane potential, cell cycle, among others, can be performed.
Advanced Light Microscopy -
IBMC - Institute for Molecular and Cell Biology
The Advance Light Microscopy (ALM) is an open access scientific core facility of IBMC dedicated to state-of the-art optical microscopy applications for biosciences. Multidimensional (6D) imaging of cells and tissues, high speed live cell microscopy, molecular analysis techniques (FRAP, FRET) and in vivo microscopy are some of the applications available to researchers
The Advance Light Microscopy (ALM) is an open access scientific core facility of IBMC dedicated to state-of the-art optical microscopy applications for biosciences. Multidimensional (6D) imaging of cells and tissues, high speed live cell microscopy, molecular analysis techniques (FRAP, FRET) and in vivo microscopy are some of the applications available to researchers
Analytical Service Unit (ASU) -
iBET - Instituto de Biologia Experimental e Tecnológica
ASU combines several services including studies on candidate pharmaceutical products (GMP), as well as analytical development, method validation and testing of chemicals and biologicals for the pharmaceutical, food and chemical industry and academia. ASU includes expertises divided by three laboratories: Analytical Lab, Mass Spectrometry Lab (iBET acess through ITQB which is one of the institutions in the National Network for Mass spectometry) and Microbiology and Bioassays Lab.
ASU combines several services including studies on candidate pharmaceutical products (GMP), as well as analytical development, method validation and testing of chemicals and biologicals for the pharmaceutical, food and chemical industry and academia. ASU includes expertises divided by three laboratories: Analytical Lab, Mass Spectrometry Lab (iBET acess through ITQB which is one of the institutions in the National Network for Mass spectometry) and Microbiology and Bioassays Lab.
Animal Cell Technology Unit -
iBET - Instituto de Biologia Experimental e Tecnológica
Specialized human resources covering all relevant scientific areas in biologics development. Top level competences in cell culture, bioprocess development, downstream processing, assay development and validation.
Specialized human resources covering all relevant scientific areas in biologics development. Top level competences in cell culture, bioprocess development, downstream processing, assay development and validation.
ANIMAL FACILITIES -
Faculty of Health Sciences, University of Beira Interior
The CICS- UBI animal Facilities comprise a quarantine room, a breeding area with rooms prepared for approximately 1600 mice and 700 rats and an experimentation area prepared also for housing mice (approximately 1000) and rats (approximately 220). All rooms are equipped with Individually ventilated cages. The experimentation area includes a surgery room. The animal facility team provides feeding, watering, daily cage changing and veterinary care.
The CICS- UBI animal Facilities comprise a quarantine room, a breeding area with rooms prepared for approximately 1600 mice and 700 rats and an experimentation area prepared also for housing mice (approximately 1000) and rats (approximately 220). All rooms are equipped with Individually ventilated cages. The experimentation area includes a surgery room. The animal facility team provides feeding, watering, daily cage changing and veterinary care.
Animal Facility -
IBMC - Institute for Molecular and Cell Biology
The IBMC/INEB AH is a breeding and experimental facility. The AH holds 2000 cages of rodents and 2 to 4 rabbits. The AH has several strains of genetically modified mice and a considerable part of it are immunocompromised rodents. The AH provides care and maintenance of GMA animais, breeding services, veterinary care and surgical support to the diferent strains and experimental models. Polyclonal antibody production is available.
The IBMC/INEB AH is a breeding and experimental facility. The AH holds 2000 cages of rodents and 2 to 4 rabbits. The AH has several strains of genetically modified mice and a considerable part of it are immunocompromised rodents. The AH provides care and maintenance of GMA animais, breeding services, veterinary care and surgical support to the diferent strains and experimental models. Polyclonal antibody production is available.
Animal Facility Unit -
Life and Health Science Research Institute (ICVS)
The ICVS has a fully equipped SPOF animal house prepared for rats, mice and guinea pigs. The facility has several rooms for animal maintenance and experimentation, equipped and prepared for surgical and experimental procedures. The animal facility team provides services of husbandry, veterinary care and animal welfare counseling. Our institution also have facilities equipped and prepared for minimally invasive surgical training and research, by using in vivo animal models as pigs and rabbits.
The ICVS has a fully equipped SPOF animal house prepared for rats, mice and guinea pigs. The facility has several rooms for animal maintenance and experimentation, equipped and prepared for surgical and experimental procedures. The animal facility team provides services of husbandry, veterinary care and animal welfare counseling. Our institution also have facilities equipped and prepared for minimally invasive surgical training and research, by using in vivo animal models as pigs and rabbits.
Animal House -
Center for Neuroscience and Cell Biology
The Animal House is a shared resource that provides services in laboratory animal experimentation and husbandry, for all CNC and FUMC scientists using animals in their research. The present facility has a capacity to house more than 3000 animals (rats/mice). This facility offers the following services: complete husbandry, including feeding, watering, daily cage changing, as well as routine procurement, inventory and care.
The Animal House is a shared resource that provides services in laboratory animal experimentation and husbandry, for all CNC and FUMC scientists using animals in their research. The present facility has a capacity to house more than 3000 animals (rats/mice). This facility offers the following services: complete husbandry, including feeding, watering, daily cage changing, as well as routine procurement, inventory and care.
Animal Model Facility -
IPATIMUP
All researchers can use these facilities to perform research with animal models. The available mice strain is produced in our Animal House: an immunodeficient mouse model, with combined immunodeficiency in T- and B-cells, which supports the growth of human and animal tumor xenografts. Their main area of application is in tumour biology and xenograft research. For more information please visit www. ipatimup.pt > Diagnostic Services > Animal Model Facility
All researchers can use these facilities to perform research with animal models. The available mice strain is produced in our Animal House: an immunodeficient mouse model, with combined immunodeficiency in T- and B-cells, which supports the growth of human and animal tumor xenografts. Their main area of application is in tumour biology and xenograft research. For more information please visit www. ipatimup.pt > Diagnostic Services > Animal Model Facility
Assay Development Unit -
BIOALVO SA
BIOALVO developed a proprietary bioactive discovery technology based on the use of yeast as a model organism–Global Platform Screening for Drug Discovery (GPS D2). This technology is extremely flexible and customizable. Depending on the desired activity, new assays can be developed for the identification of new ingredients/molecules with proven potency and safety.BIOALVO has already implemented assays for a wide range of markets, such as cosmetic, pharmaceutical, nutrition and household products
BIOALVO developed a proprietary bioactive discovery technology based on the use of yeast as a model organism–Global Platform Screening for Drug Discovery (GPS D2). This technology is extremely flexible and customizable. Depending on the desired activity, new assays can be developed for the identification of new ingredients/molecules with proven potency and safety.BIOALVO has already implemented assays for a wide range of markets, such as cosmetic, pharmaceutical, nutrition and household products
Bioinstrumentation Laboratory -
INESC TEC
The main goal of the Bioinstrumentation lab is to perform high-level interdisciplinary R&D in engineering and computational approaches applied to health, well-being, rehabilitation and sports performance, namely crossing several areas, such as Physics. Engineering (Electronics, Computation, Signal Processing), Physiology, Physiotherapy, Psychophysics, Sports and Human Movement sciences.
The main goal of the Bioinstrumentation lab is to perform high-level interdisciplinary R&D in engineering and computational approaches applied to health, well-being, rehabilitation and sports performance, namely crossing several areas, such as Physics. Engineering (Electronics, Computation, Signal Processing), Physiology, Physiotherapy, Psychophysics, Sports and Human Movement sciences.
Biological and Chemical Analysis Facility -
UCIBIO, Universidade Nova de Lisboa, Universidade do Porto
The BioLab is a Biological and Chemical Analysis Facility at FCT-NOVA. This facility is devoted to the comprehension of cellular and molecular mechanisms, from the in vitro characterization of molecular interactions to the in vivo validation in model animals. The BioLab facility gathers in a single unit a unique set of state-of-the-art biophysical and biological technologies. For a complete characterization of your biological/chemical system please contact us biolab@campus.fct.unl.pt.
The BioLab is a Biological and Chemical Analysis Facility at FCT-NOVA. This facility is devoted to the comprehension of cellular and molecular mechanisms, from the in vitro characterization of molecular interactions to the in vivo validation in model animals. The BioLab facility gathers in a single unit a unique set of state-of-the-art biophysical and biological technologies. For a complete characterization of your biological/chemical system please contact us biolab@campus.fct.unl.pt.
Biomechanics of Biological Tissues -
INEGI - Institute of Science and Innovation in Mechanical and Industrial Engineering
This service centre provides for high quality experimental data in the mechanical characterization of biological tissues.
This service centre provides for high quality experimental data in the mechanical characterization of biological tissues.
Biomedical Imaging Laboratory -
INESC TEC
The main focus of the Biomedical Imaging Lab is the development of advanced image processing and analysis methodologies, particularly medical and biological images, with the aim of creating Computer-aided Diagnosis (CAD) tools to support medical decision making. The research activities at the Lab use several imaging modalities addressing different clinical departments including in Ophthalmology, Radiology, Gynaecology, Obstetrics, Cardiology and Gastroenterology.
The main focus of the Biomedical Imaging Lab is the development of advanced image processing and analysis methodologies, particularly medical and biological images, with the aim of creating Computer-aided Diagnosis (CAD) tools to support medical decision making. The research activities at the Lab use several imaging modalities addressing different clinical departments including in Ophthalmology, Radiology, Gynaecology, Obstetrics, Cardiology and Gastroenterology.
Biosafety Level 3 Security -
iMed.ULisboa/ FFULisboa Research Institute for Medicines/ Faculdade de Farmácia, Universidade de Lisboa
This facility is specifically dedicated to research involving biological pathogens of level 3. It was designed to minimize the risk of personnel and environmental exposure to potential hazardous agents according to European and Portuguese legislation.
This facility is specifically dedicated to research involving biological pathogens of level 3. It was designed to minimize the risk of personnel and environmental exposure to potential hazardous agents according to European and Portuguese legislation.
Biosafety Level 3 Unit of Specialized Services (BSL3 USS) -
Life and Health Science Research Institute (ICVS)
The BSL3 USS is composed by a Biosafety Committee and Biosaftey Coordinators to assure that the European and International guidelines of biosafety and biosecurity are fulfilled. The BSL3 USS also provides education, training, and guidance for researchers. The BSL3 USS allows in vitro and in vivo experimentation involving biosafety level 3 pathogens. The BSL3 USS is fully equipped with tissue culture rooms and animal experimentation rooms for mice and guinea pigs.
The BSL3 USS is composed by a Biosafety Committee and Biosaftey Coordinators to assure that the European and International guidelines of biosafety and biosecurity are fulfilled. The BSL3 USS also provides education, training, and guidance for researchers. The BSL3 USS allows in vitro and in vivo experimentation involving biosafety level 3 pathogens. The BSL3 USS is fully equipped with tissue culture rooms and animal experimentation rooms for mice and guinea pigs.
Biostatistics | Pharmacoeconomics -
Eurotrials, Consultores Científicos, S.A.
The department of Bioestatistics provides a wide range of services adapted to the needs of each project. Statistical advice, study reports and assistance in preparing articles for biomedical journals are examples. It also ensures correct methodological development and appropriate planning in clinical trials and guarantees the quality of protocols and reliable data processing, all of which are crucial to the success of any research project.
The department of Bioestatistics provides a wide range of services adapted to the needs of each project. Statistical advice, study reports and assistance in preparing articles for biomedical journals are examples. It also ensures correct methodological development and appropriate planning in clinical trials and guarantees the quality of protocols and reliable data processing, all of which are crucial to the success of any research project.
Biotério -
Faculdade de Medicina da Universidade do Porto
Biotério is an Animal Facility that houses laboratory animals used in research.There are 23 animal maintenance rooms which can house mouse, rat, guineapigs, rabbits, and fish, among others, in a conventional environment or in specific pathogen-free conditions. The technical team consists of four animal caretakers, a technical assistant and a veterinary.
Biotério is an Animal Facility that houses laboratory animals used in research.There are 23 animal maintenance rooms which can house mouse, rat, guineapigs, rabbits, and fish, among others, in a conventional environment or in specific pathogen-free conditions. The technical team consists of four animal caretakers, a technical assistant and a veterinary.
Biotério – Animal Facilities -
iMed.ULisboa/ FFULisboa Research Institute for Medicines/ Faculdade de Farmácia, Universidade de Lisboa
The Faculdade de Farmácia, Universidade de Lisboa (FFUL) has an animal facility for rodents with a capacity to house around 500 rats/mice, which supports R&D activities at iMed.UL. The facility has several rooms for animal maintenance and experimentation prepared for surgical and experimental procedures. The animal house provides support on protocol development and licensing, refinement and advice in experimental procedures and simple surgical techniques by certified researchers.
The Faculdade de Farmácia, Universidade de Lisboa (FFUL) has an animal facility for rodents with a capacity to house around 500 rats/mice, which supports R&D activities at iMed.UL. The facility has several rooms for animal maintenance and experimentation prepared for surgical and experimental procedures. The animal house provides support on protocol development and licensing, refinement and advice in experimental procedures and simple surgical techniques by certified researchers.
Bloco Instrumental (BI) -
iMed.ULisboa/ FFULisboa Research Institute for Medicines/ Faculdade de Farmácia, Universidade de Lisboa
The BI (Bloco Instrumental) is an analytical laboratory located at the Faculty of Pharmacy, University of Lisbon. BI provides services on development and implementation of different analytical methods, for the academia or external institutions. It was designed to support the pharmaceutical industry, but it also supports food, cosmetics and chemical industries as well as environmental control.
The BI (Bloco Instrumental) is an analytical laboratory located at the Faculty of Pharmacy, University of Lisbon. BI provides services on development and implementation of different analytical methods, for the academia or external institutions. It was designed to support the pharmaceutical industry, but it also supports food, cosmetics and chemical industries as well as environmental control.
Blueclinical Clinical Research Partnership -
Blueclinical Ltd
Blueclinical CRP is a network of hospitals and primary care centers that serve about 5 million people. All clinical research related activities are performed under a quality management system. This system aims to document and standardize, by means of written standard operating procedures, all the critical clinical research activities, in order to maximize the efficiency of the processes and to assure full compliance with good clinical practices and the legal and ethical requirements.
Blueclinical CRP is a network of hospitals and primary care centers that serve about 5 million people. All clinical research related activities are performed under a quality management system. This system aims to document and standardize, by means of written standard operating procedures, all the critical clinical research activities, in order to maximize the efficiency of the processes and to assure full compliance with good clinical practices and the legal and ethical requirements.
Blueclinical Phase I -
Blueclinical Ltd
Blueclinical Phase I is a private and independent clinical research unit devoted to the conduct of studies in healthy subjects and early proof-of-concept studies in selected patient populations. Clinical research activities are performed in an exclusive and dedicated 29-bed unit by Blueclinical Phase I’s own staff, which has a wide and long experience in phase I studies in healthy subjects, including pharmacokinetics, drug interactions, food effect and bioavailability/bioequivalence studies.
Blueclinical Phase I is a private and independent clinical research unit devoted to the conduct of studies in healthy subjects and early proof-of-concept studies in selected patient populations. Clinical research activities are performed in an exclusive and dedicated 29-bed unit by Blueclinical Phase I’s own staff, which has a wide and long experience in phase I studies in healthy subjects, including pharmacokinetics, drug interactions, food effect and bioavailability/bioequivalence studies.
Bn'ML-Behavioral and Molecular Lab -
Life and Health Science Research Institute (ICVS)
Bn’ML company provides behavioral and molecular analysis services for both the academia and industry to assess the therapeutic potential of new compounds, using animal models of disease. Our services include: a flexible design of the study to evaluate the therapeutic potential of new compounds; the induction of the disease symptoms in animals; the administration of the compounds in animals; the evaluation of the therapeutic potential of the compounds at the behavioral and molecular levels.
Bn’ML company provides behavioral and molecular analysis services for both the academia and industry to assess the therapeutic potential of new compounds, using animal models of disease. Our services include: a flexible design of the study to evaluate the therapeutic potential of new compounds; the induction of the disease symptoms in animals; the administration of the compounds in animals; the evaluation of the therapeutic potential of the compounds at the behavioral and molecular levels.
C. elegans Shared Facility (ElegantLab) -
Life and Health Science Research Institute (ICVS)
The ElegantLab is a combination of two rooms with controlled temperature and fully equipped to maintain and handle the animal model Caenorhabditis elegans. The research focus of this facility is mainly related to a better understanding of neurodevelopmental and neurodegenerative disease mechanisms, as well as to search for therapeutic strategies.
The ElegantLab is a combination of two rooms with controlled temperature and fully equipped to maintain and handle the animal model Caenorhabditis elegans. The research focus of this facility is mainly related to a better understanding of neurodevelopmental and neurodegenerative disease mechanisms, as well as to search for therapeutic strategies.
CEC - Clinical Trial Centre -
AIBILI - Association for Innovation and Biomedical Research on Light and Image
The Clinical Trial Centre (CEC) performs clinical studies. CEC has dedicated facilities and updated ophthalmological equipment. Clinical patient-oriented research involves characterizing disease progression and testing new discoveries by carrying out carefully controlled research studies in patients, i. e., clinical trials. This includes testing not only new drugs, but also new methods, devices, imaging and surgical procedures as well as prospective, observational, longitudinal studies.
The Clinical Trial Centre (CEC) performs clinical studies. CEC has dedicated facilities and updated ophthalmological equipment. Clinical patient-oriented research involves characterizing disease progression and testing new discoveries by carrying out carefully controlled research studies in patients, i. e., clinical trials. This includes testing not only new drugs, but also new methods, devices, imaging and surgical procedures as well as prospective, observational, longitudinal studies.
Cell Biology -
BIOCANT - Biotechnology Innovation Center
The Cell Culture facility is specialized in cell culture in general, isolation of stem cells from the umbilical cord, cell viability assays and cellular characterization. It is mainly focused on running R&D projects in collaboration with research institutions and biotech companies. We also provide a Multiplex Serology Service specialized in the quantification of biomarkers, especially proteins in tissues and fluids.
The Cell Culture facility is specialized in cell culture in general, isolation of stem cells from the umbilical cord, cell viability assays and cellular characterization. It is mainly focused on running R&D projects in collaboration with research institutions and biotech companies. We also provide a Multiplex Serology Service specialized in the quantification of biomarkers, especially proteins in tissues and fluids.
Cell Biology -
iMed.ULisboa/ FFULisboa Research Institute for Medicines/ Faculdade de Farmácia, Universidade de Lisboa
This facility is dedicated to the analysis of gene expression at DNA, RNA and protein level, routinely performing a multitude of biochemical and molecular biology techniques using standard equipment for electrophoresis, western blot, northern bot, as well absorbance plate reader, and gel, membrane and X-ray film imaging (Chemidoc MP and XRS; Bio-Rad).
This facility is dedicated to the analysis of gene expression at DNA, RNA and protein level, routinely performing a multitude of biochemical and molecular biology techniques using standard equipment for electrophoresis, western blot, northern bot, as well absorbance plate reader, and gel, membrane and X-ray film imaging (Chemidoc MP and XRS; Bio-Rad).
Cell Culture and Genotyping -
IBMC - Institute for Molecular and Cell Biology
Cooperates with researchers to improve cell culture conditions, genotyping, gene expression techniques and offers technical assistance to researchers. Offers individual fully equipped and monitored rooms for cell culture, mycoplasma tests and a monitored N2 reservoir for cell storage. Facilitates the implementation of genotyping and gene expression technology including expert consultation and training, by providing equipment for gene expression analysis; automated DNA and RNA extraction; quantif
Cooperates with researchers to improve cell culture conditions, genotyping, gene expression techniques and offers technical assistance to researchers. Offers individual fully equipped and monitored rooms for cell culture, mycoplasma tests and a monitored N2 reservoir for cell storage. Facilitates the implementation of genotyping and gene expression technology including expert consultation and training, by providing equipment for gene expression analysis; automated DNA and RNA extraction; quantif
Cell Function -
iMed.ULisboa/ FFULisboa Research Institute for Medicines/ Faculdade de Farmácia, Universidade de Lisboa
The facility is tailored for biological evaluation of cell function, routinely determining cytotoxic and cytoprotective activities of synthetic and natural compounds, in multiple cell models, including immortalized and primary cultures and stem cells, with implemented capability of cell function assays up to 96 and 384-well format.
The facility is tailored for biological evaluation of cell function, routinely determining cytotoxic and cytoprotective activities of synthetic and natural compounds, in multiple cell models, including immortalized and primary cultures and stem cells, with implemented capability of cell function assays up to 96 and 384-well format.
Center for Clinical Investigation -
Centro Hospitalar Cova da Beira EPE
CHCB is an interdisciplinary research platform on which scientists/clinicians are able to exchange scientific information and create collaborations to develop and improve health care. CHCB is well equipped with technical facilities that enable the production of diagnostic and therapeutic tests,laboratory tests,imaging,surgical services,acute care and palliative services.It is highly sought not only for academic research but also for clinical trials,observational studies and experimental studies.
CHCB is an interdisciplinary research platform on which scientists/clinicians are able to exchange scientific information and create collaborations to develop and improve health care. CHCB is well equipped with technical facilities that enable the production of diagnostic and therapeutic tests,laboratory tests,imaging,surgical services,acute care and palliative services.It is highly sought not only for academic research but also for clinical trials,observational studies and experimental studies.
Center for Predictive and Preventive Genetics -
IBMC - Institute for Molecular and Cell Biology
At the outpatient clinic, patients and families with genetic diseases are observed and counselled by a multi-disciplinary team. At our molecular genetics lab, diagnostic, carrier, presymptomatic and prenatal tests are available for a large number of diseases. A quality management system is in place, and a formal request for accreditation has already been filed to IPAQ. The DNA/cell-line bank storages many thousands of samples, coupled with clinical and pedigree data.
At the outpatient clinic, patients and families with genetic diseases are observed and counselled by a multi-disciplinary team. At our molecular genetics lab, diagnostic, carrier, presymptomatic and prenatal tests are available for a large number of diseases. A quality management system is in place, and a formal request for accreditation has already been filed to IPAQ. The DNA/cell-line bank storages many thousands of samples, coupled with clinical and pedigree data.
Centro de Farmacovigilância do Sul -
iMed.ULisboa/ FFULisboa Research Institute for Medicines/ Faculdade de Farmácia, Universidade de Lisboa
This facility provides competencies raging from reception, validation, analysis and evaluation of suspected adverse drug reactions, dissemination of pharmacovigilance in the southern region of the country and training in pharmacovigilance field, to scientific activity and research related to drug use safety.
This facility provides competencies raging from reception, validation, analysis and evaluation of suspected adverse drug reactions, dissemination of pharmacovigilance in the southern region of the country and training in pharmacovigilance field, to scientific activity and research related to drug use safety.
CHAD – Health Technology Assessment and Drug Research -
AIBILI - Association for Innovation and Biomedical Research on Light and Image
The Centre for Health Technology Assessment and Drug Research (CHAD) focus is on evaluation of medicines and other medicinal products for market access purposes, aiming at financing and reimbursement, pharmacovigilance and bioequivalence studies for generic drugs approval and drug safety monitoring.
The Centre for Health Technology Assessment and Drug Research (CHAD) focus is on evaluation of medicines and other medicinal products for market access purposes, aiming at financing and reimbursement, pharmacovigilance and bioequivalence studies for generic drugs approval and drug safety monitoring.
Chromatography, LC and GC -
Hovione FarmaCiencia SA
The Chromatography Service integrates multidimensional and hyphenated technologies to perform advance Method Development, Method Validation, In process Control and Final product Release analysis, Standard Qualification and Requalification, Impurity Screening and Characterization. All services provided within the Chromatography area are all under current Good Manufacturing Practices and using Full Qualified Analytical Systems.
The Chromatography Service integrates multidimensional and hyphenated technologies to perform advance Method Development, Method Validation, In process Control and Final product Release analysis, Standard Qualification and Requalification, Impurity Screening and Characterization. All services provided within the Chromatography area are all under current Good Manufacturing Practices and using Full Qualified Analytical Systems.
Clinical Trials -
Eurotrials, Consultores Científicos, S.A.
Eurotrials develops and monitors clinical research projects in Europe and Latin America. The team has vast experience in managing studies on both sides of the Atlantic. At the forefront with clinical research sites, we develop the capacity building projects for integration in International Networks of Excellence and R&D platforms.
Eurotrials develops and monitors clinical research projects in Europe and Latin America. The team has vast experience in managing studies on both sides of the Atlantic. At the forefront with clinical research sites, we develop the capacity building projects for integration in International Networks of Excellence and R&D platforms.
CLINICAL TRIALS -
Clinical Academic Center – Braga, Association (CCAB)
A clinical trial requires skills from many different types of experts. In this context, the 2CA-Braga team is composed of clinicians, researchers, nurses, study coordinators, pharmacists, imaging technicians, data managers and support staff.
A clinical trial requires skills from many different types of experts. In this context, the 2CA-Braga team is composed of clinicians, researchers, nurses, study coordinators, pharmacists, imaging technicians, data managers and support staff.
CNTM - Centre of New Technologies for Medicine -
AIBILI - Association for Innovation and Biomedical Research on Light and Image
The Centre of New Technologies for Medicine (CNTM) develops new medical diagnostic techniques with special emphasis on the area of eye fundus imaging. CNTM has developed the concept of Multimodal Macula Mapping and has been developing new tools to correlate information obtained from sequential fundus imaging and automatic lesion detection.The ultimate goal of CNTM is innovation in eye imaging and transfer these technological innovations to Industry and, therefore, to the market.
The Centre of New Technologies for Medicine (CNTM) develops new medical diagnostic techniques with special emphasis on the area of eye fundus imaging. CNTM has developed the concept of Multimodal Macula Mapping and has been developing new tools to correlate information obtained from sequential fundus imaging and automatic lesion detection.The ultimate goal of CNTM is innovation in eye imaging and transfer these technological innovations to Industry and, therefore, to the market.
Computer Assisted Drug Design -
iMed.ULisboa/ FFULisboa Research Institute for Medicines/ Faculdade de Farmácia, Universidade de Lisboa
The laboratory for Advanced Molecular Modeling at Faculty of Pharmacy from the University of Lisbon provides resources to scientists or enterprises performing research which needs high-performance computing and storage. LAMM also provides consulting, documentation and training for users of these resources (hardware and software).
The laboratory for Advanced Molecular Modeling at Faculty of Pharmacy from the University of Lisbon provides resources to scientists or enterprises performing research which needs high-performance computing and storage. LAMM also provides consulting, documentation and training for users of these resources (hardware and software).
CORC – Coimbra Ophthalmology Reading Centre -
AIBILI - Association for Innovation and Biomedical Research on Light and Image
The Coimbra Ophthalmology Reading Centre (CORC) focus its activities in grading fundus images and OCT images of the retina, as well as functional evaluations of the retina using mfERG. It serves as central Reading Centre for a series of multinational and multicentric clinical studies, mainly in Diabetic Retinopathy (DR) and Age-related Macular Degeneration (AMD), some of them performed within the EVICR.net.
The Coimbra Ophthalmology Reading Centre (CORC) focus its activities in grading fundus images and OCT images of the retina, as well as functional evaluations of the retina using mfERG. It serves as central Reading Centre for a series of multinational and multicentric clinical studies, mainly in Diabetic Retinopathy (DR) and Age-related Macular Degeneration (AMD), some of them performed within the EVICR.net.
CYTOMETRY LABORATORY -
Faculty of Health Sciences, University of Beira Interior
This laboratory (24 m2) is equipped with a flow cytometer FACScalibur (4 colors), and a high-speed analyzer CyAn (Beckam Coulter) that can measure up to 9 colors. These instruments allow us to analyze biological cells, beads or other microscopic particles. With their multi-color capabilities, a wide range of flow cytometric research and clinical demands can be performed, such as immunophenotyping and cell viability analysis. Additionally, there is an AutoMACS cell separator (BD).
This laboratory (24 m2) is equipped with a flow cytometer FACScalibur (4 colors), and a high-speed analyzer CyAn (Beckam Coulter) that can measure up to 9 colors. These instruments allow us to analyze biological cells, beads or other microscopic particles. With their multi-color capabilities, a wide range of flow cytometric research and clinical demands can be performed, such as immunophenotyping and cell viability analysis. Additionally, there is an AutoMACS cell separator (BD).
Data Management -
Eurotrials, Consultores Científicos, S.A.
The team uses cutting-edge technology in electronic data collection and is more competitive in undertaking projects. The integration of these processes with Eurotrials’ data management system, which has been validated and is in strict compliance with FDA 21 CFR part 11, is an essential asset.
The team uses cutting-edge technology in electronic data collection and is more competitive in undertaking projects. The integration of these processes with Eurotrials’ data management system, which has been validated and is in strict compliance with FDA 21 CFR part 11, is an essential asset.
DATA MANAGEMENT -
Clinical Academic Center – Braga, Association (CCAB)
The CCAB informatics department, in partnership with the CCAB team, combines various skills with the purpose of develop and execute specialized techniques to data management.
The CCAB informatics department, in partnership with the CCAB team, combines various skills with the purpose of develop and execute specialized techniques to data management.
Data Management / Statistics / Medical Writing -
Lean Data Consulting, Lda.
From defining the study protocol and the information to be collected, to exporting data for statistical analysis, we focus on the essential of each project. We work to minimize the timing between the processes of data collection and data analysis, with a high standard of quality, always complying with our client's goals. We want to reduce the levels of uncertainty associated with data on which our client's decisions are based, justifying the investment made in each stage preceding data analysis.
From defining the study protocol and the information to be collected, to exporting data for statistical analysis, we focus on the essential of each project. We work to minimize the timing between the processes of data collection and data analysis, with a high standard of quality, always complying with our client's goals. We want to reduce the levels of uncertainty associated with data on which our client's decisions are based, justifying the investment made in each stage preceding data analysis.
Dentistry Platform -
Faculty of Medicine, University of Coimbra
In this service scientific research is carried out in tree Laboratories: Mechanical Testing, Hard Tissue and Forensic Dentistry. In the first, samples are prepared for various tests and methods of analysis, Aging and thermal and chemical fatigue of samples and materials can be performed. In the second they can perform the processing of biological samples following calcified and decalcified techniques. In the third a service of dentistry medical-legal expertise is provided.
In this service scientific research is carried out in tree Laboratories: Mechanical Testing, Hard Tissue and Forensic Dentistry. In the first, samples are prepared for various tests and methods of analysis, Aging and thermal and chemical fatigue of samples and materials can be performed. In the second they can perform the processing of biological samples following calcified and decalcified techniques. In the third a service of dentistry medical-legal expertise is provided.
Drug Product Evaluation -
Hovione FarmaCiencia SA
The Service Centre Drug Product Evaluation performs the analysis of all products that are involved in the processes of drug product production and development, from the Active Pharmaceutical Ingredient (APIs) until the final drug product, for both oral solid dosage forms and inhalation products. This Service also performs development, validation of analytical methods, in process support, analytical support to galenic development and stability studies. The Service provides physical characterization of powders.
The Service Centre Drug Product Evaluation performs the analysis of all products that are involved in the processes of drug product production and development, from the Active Pharmaceutical Ingredient (APIs) until the final drug product, for both oral solid dosage forms and inhalation products. This Service also performs development, validation of analytical methods, in process support, analytical support to galenic development and stability studies. The Service provides physical characterization of powders.
Electron Microscopy -
Instituto Gulbenkian de Ciência
The Electron Microscopy Facility is part of the shared facilities at the Instituto Gulbenkian de Ciência, Oeiras, Portugal. The facility provides centralized, high-quality room temperature transmission electron microscopy techniques and resources for all researchers at the Instituto Gulbenkian de Ciência and within the Portuguese Research Community. Capabilities include conventional and cryo sample preservation, room temperature and cryo-sectioning and room temperature TEM.
The Electron Microscopy Facility is part of the shared facilities at the Instituto Gulbenkian de Ciência, Oeiras, Portugal. The facility provides centralized, high-quality room temperature transmission electron microscopy techniques and resources for all researchers at the Instituto Gulbenkian de Ciência and within the Portuguese Research Community. Capabilities include conventional and cryo sample preservation, room temperature and cryo-sectioning and room temperature TEM.
Epidemiology & Late Phase Research -
Eurotrials, Consultores Científicos, S.A.
With more than 350,000 individuals included in its studies, Eurotrials is able to meet the specific needs and requirements of an increasingly demanding area. The existence/availability of Epidemiological data and Post-commercialisation Studies data are crucial in validating Scientific, Therapeutic, Economic and Healthcare Policy solutions. Eurotrials uses cutting edge and technologically innovative solutions to gather information and accompanying data about its projects.
With more than 350,000 individuals included in its studies, Eurotrials is able to meet the specific needs and requirements of an increasingly demanding area. The existence/availability of Epidemiological data and Post-commercialisation Studies data are crucial in validating Scientific, Therapeutic, Economic and Healthcare Policy solutions. Eurotrials uses cutting edge and technologically innovative solutions to gather information and accompanying data about its projects.
EVICR.net Coordinating Centre -
AIBILI - Association for Innovation and Biomedical Research on Light and Image
AIBILI is the headquarters and Coordinating Centre of the European Vision Institute Clinical Research Network – EVICR.net. EVICR.net is a network of European Ophthalmological Clinical Research Sites, dedicated to perform clinical research in ophthalmology. EVICR.net is a platform for clinical trial research in ophthalmology in Europe and a useful Industry resource in order to promote the development of new drugs and medical devices.
AIBILI is the headquarters and Coordinating Centre of the European Vision Institute Clinical Research Network – EVICR.net. EVICR.net is a network of European Ophthalmological Clinical Research Sites, dedicated to perform clinical research in ophthalmology. EVICR.net is a platform for clinical trial research in ophthalmology in Europe and a useful Industry resource in order to promote the development of new drugs and medical devices.
Flow Cytometry Shared Facility (FlowSF) -
Life and Health Science Research Institute (ICVS)
The FlowSF is equipped to high standards for cell analysis and enrichment by flow cytometry. Available equipment includes a LSRII (prepared to simultaneously read 8 different colors), a FACS Calibur and a AutoMACS Cell separator. The facility is prepared to analyze animal and human cells; the use of other cell types should be proposed to the FlowSF and optimized by the user. New users need specific training and previous approval before independently using the facilities.
The FlowSF is equipped to high standards for cell analysis and enrichment by flow cytometry. Available equipment includes a LSRII (prepared to simultaneously read 8 different colors), a FACS Calibur and a AutoMACS Cell separator. The facility is prepared to analyze animal and human cells; the use of other cell types should be proposed to the FlowSF and optimized by the user. New users need specific training and previous approval before independently using the facilities.
Flow Cytometry Unit -
Center for Neuroscience and Cell Biology
The Flow Cytometry Unit provides technical support on flow cytometry. Currently, it is equipped with a Becton Dickinson FACSCalibur cell analyser and a Partec CyFlow Space cell sorter. The cytometry unit provides scientific and technical support for those wishing to use flow cytometry in their studies and is available to all CNC researchers, as well for those external to the CNC, after prior arrangement.
The Flow Cytometry Unit provides technical support on flow cytometry. Currently, it is equipped with a Becton Dickinson FACSCalibur cell analyser and a Partec CyFlow Space cell sorter. The cytometry unit provides scientific and technical support for those wishing to use flow cytometry in their studies and is available to all CNC researchers, as well for those external to the CNC, after prior arrangement.
FLUORESCENCE MICROSCOPY LABORATORY -
Faculty of Health Sciences, University of Beira Interior
This laboratory (31 m2) is presently equipped with an inverted Zeiss axioObserver microscope prepared to perform live imaging and also a confocal microscope AxioObserver LSM 710. These systems are prepared to perform FRET analysis and calcium imaging and are equipped with micromanipulators and microinjectors.
This laboratory (31 m2) is presently equipped with an inverted Zeiss axioObserver microscope prepared to perform live imaging and also a confocal microscope AxioObserver LSM 710. These systems are prepared to perform FRET analysis and calcium imaging and are equipped with micromanipulators and microinjectors.
Formulation development -
Inovapotek, Lda
We start by looking for the best active ingredients and excipients to use, designing a theoretical formulation for each product.Then, the experimental procedure takes place and formulations are optimized according to organoleptic and sensorial characteristics, preliminary stability studies and of course, according to the client’s input.
We start by looking for the best active ingredients and excipients to use, designing a theoretical formulation for each product.Then, the experimental procedure takes place and formulations are optimized according to organoleptic and sensorial characteristics, preliminary stability studies and of course, according to the client’s input.
FTIR and Mass Spectrometry -
Faculdade de Ciências da Universidade de Lisboa
The laboratory of FTICR-MS and Structural Mass Spectrometry provides the highest performance technology for problem solving in health and life sciences. Provides support to food and wine industry, forensics and fundamental research in chemistry, biochemistry and biology. It is the main laboratory of the Portuguese Mass Spectrometry Network, a National Roadmap Research Infrastructure of Strategic Interest.
The laboratory of FTICR-MS and Structural Mass Spectrometry provides the highest performance technology for problem solving in health and life sciences. Provides support to food and wine industry, forensics and fundamental research in chemistry, biochemistry and biology. It is the main laboratory of the Portuguese Mass Spectrometry Network, a National Roadmap Research Infrastructure of Strategic Interest.
GENOINSEQ -
BIOCANT - Biotechnology Innovation Center
Genoinseq grants access to the full potential of state-of-the-art of next generation sequencing equipment, high throughput genotyping and bioinformatics data analysis. Genoinseq provides services or collaborates in R&D projects with companies and research groups. The unit has a multidisciplinary team of experts in sequencing and bioinformatics, delivering personalized solutions, from consultancy in experimental design to large scale data analysis with user-friendly outputs.
Genoinseq grants access to the full potential of state-of-the-art of next generation sequencing equipment, high throughput genotyping and bioinformatics data analysis. Genoinseq provides services or collaborates in R&D projects with companies and research groups. The unit has a multidisciplinary team of experts in sequencing and bioinformatics, delivering personalized solutions, from consultancy in experimental design to large scale data analysis with user-friendly outputs.
GMP Manufacturing - Cells and Cell based Products -
Stemmatters, Biotecnologia e Medicina Regenerativa SA
Stemmatters provides cGMP services regarding tissue processing, manufacturing and banking (cells and cell based products).The facility comprises 250 m2 of qualified controlled environment rooms (CERs) and material pass-boxes. Our quality management system ensures that our products are consistently produced and controlled according to strict quality standards (EU-GMP Guide/ICH Q7 and ISO 9001:2008).We work with specialized distribution networks to assure high quality according to GMP guidelines.
Stemmatters provides cGMP services regarding tissue processing, manufacturing and banking (cells and cell based products).The facility comprises 250 m2 of qualified controlled environment rooms (CERs) and material pass-boxes. Our quality management system ensures that our products are consistently produced and controlled according to strict quality standards (EU-GMP Guide/ICH Q7 and ISO 9001:2008).We work with specialized distribution networks to assure high quality according to GMP guidelines.
Histology and Electron Microscopy Service -
IBMC - Institute for Molecular and Cell Biology
This Core Research Facility is centered on Transmission Electronic Microscopy and Optical Microscopy with the ancillary equipment. Provides both the equipment and technical support to researchers needing high level optical and TEM to tackle studies either of cell or material sciences. Besides the instruction of researchers the Facility also offers training courses as well as guided visits to high school students. Facility is engaged on workshops or exhibitions for the public organized by IBMC.
This Core Research Facility is centered on Transmission Electronic Microscopy and Optical Microscopy with the ancillary equipment. Provides both the equipment and technical support to researchers needing high level optical and TEM to tackle studies either of cell or material sciences. Besides the instruction of researchers the Facility also offers training courses as well as guided visits to high school students. Facility is engaged on workshops or exhibitions for the public organized by IBMC.
Histology Shared Technical Facility (HistoSTF) -
Life and Health Science Research Institute (ICVS)
HistoSTF combines several services in the development and execution of specialized histology techniques to industry and academia. The HistoSTF is composed of a team of 3 specialized lab technicians and is fully equipped for providing services in paraffin and methacrylate embedding tissues, frozen and vibratome sectioning and routine stains.
HistoSTF combines several services in the development and execution of specialized histology techniques to industry and academia. The HistoSTF is composed of a team of 3 specialized lab technicians and is fully equipped for providing services in paraffin and methacrylate embedding tissues, frozen and vibratome sectioning and routine stains.
ICVS Cell Culture Services (ICVS-CCS) -
Life and Health Science Research Institute (ICVS)
ICVS Cell Culture Services (ICVS-CCS) provides a range of services related with cell culture, including Bio-banking, Cell Assays and Consulting.
ICVS Cell Culture Services (ICVS-CCS) provides a range of services related with cell culture, including Bio-banking, Cell Assays and Consulting.
In Ovo Technical Service (InOvoTS) -
Life and Health Science Research Institute (ICVS)
InOvoTS combines several services in the development and execution of specialized in vivo techniques designed for industry and academia using the chick in ovo model. The InOvoTS is supervised by 2 senior researches with complementary scientific backgrounds and is fully prepared to provide technical expertise and/or full services on multiple studies employing the chick in ovo model. These include the evaluation of biocompatibility/toxicology/anti-tumor properties of novel drugs/compounds.
InOvoTS combines several services in the development and execution of specialized in vivo techniques designed for industry and academia using the chick in ovo model. The InOvoTS is supervised by 2 senior researches with complementary scientific backgrounds and is fully prepared to provide technical expertise and/or full services on multiple studies employing the chick in ovo model. These include the evaluation of biocompatibility/toxicology/anti-tumor properties of novel drugs/compounds.
In vivo CAM assays (IPATIMUP/Expertus) -
IPATIMUP
Expertus, in vivo CAM assays is a spin-off of IPATIMUP that supplies a range of innovative custom made chicken embryo CAM (choriallantoic membrane) assays, as services for cancer research and anti-cancer drug screening. Specifically, CAM assays for the evaluation of angiogenesis (induced by cells and/or drugs), tumorigenesis and invasion.
Expertus, in vivo CAM assays is a spin-off of IPATIMUP that supplies a range of innovative custom made chicken embryo CAM (choriallantoic membrane) assays, as services for cancer research and anti-cancer drug screening. Specifically, CAM assays for the evaluation of angiogenesis (induced by cells and/or drugs), tumorigenesis and invasion.
IPATIMUP Diagnostics -
IPATIMUP
Its mission is to provide optimal services of surgical pathology and cytopathology, molecular pathology, genetic diagnosis, and parentage and genetic identification. This Unit is accredited by the College of American Pathologists, while it is enrolled in other Quality Control Programs. It has state-of-the-art equipment, namely a Next Generation platform. It is a reference center for several pharmaceutical companies for specific analysis and works with most of the main Portuguese Hospitals.
Its mission is to provide optimal services of surgical pathology and cytopathology, molecular pathology, genetic diagnosis, and parentage and genetic identification. This Unit is accredited by the College of American Pathologists, while it is enrolled in other Quality Control Programs. It has state-of-the-art equipment, namely a Next Generation platform. It is a reference center for several pharmaceutical companies for specific analysis and works with most of the main Portuguese Hospitals.
Laboratório Nobre -
Faculdade de Medicina da Universidade do Porto
O Laboratório Nobre destina-se a apoiar o desenvolvimento de projetos de investigação na área da Bioquímica de toda a comunidade académica e clínica da Faculdade de Medicina, do Centro Hospitalar de São João, e de outras instituições.
O Laboratório Nobre destina-se a apoiar o desenvolvimento de projetos de investigação na área da Bioquímica de toda a comunidade académica e clínica da Faculdade de Medicina, do Centro Hospitalar de São João, e de outras instituições.
Laboratory for High-Resolution Cellular Bio-Imaging -
Faculty of Medicine, University of Coimbra
The high resolution cellular bio-imaging laboratory is a technological platform managed by the Faculty of Medicine of the University of Coimbra (FMUC). It is part of the National Network of Electron Microscopy (Pole of the University of Coimbra - RNME) and the only technological infrastructure of transmission electron microscopy (TEM), in the center of Portugal, specially dedicated to the Health Sciences field.
The high resolution cellular bio-imaging laboratory is a technological platform managed by the Faculty of Medicine of the University of Coimbra (FMUC). It is part of the National Network of Electron Microscopy (Pole of the University of Coimbra - RNME) and the only technological infrastructure of transmission electron microscopy (TEM), in the center of Portugal, specially dedicated to the Health Sciences field.
Laboratory for Indoor Air Quality -
INEGI - Institute of Science and Innovation in Mechanical and Industrial Engineering
This service centre provides for indoor air quality control.
This service centre provides for indoor air quality control.
Laboratory of Microscopic and Ultramicroscopic Imagiology (LIMU) -
Faculdade de Medicina da Universidade do Porto
O LIMU (Laboratório de Imagiologia Microscópica e Ultramicroscópica) faz estudos de microscopia e imagiologia avançada de células e tecidos. Tem equipamento para realizar todos os procedimentos laboratoriais necessários à preparação de amostras para microscopia ótica e para microscopia eletrónica de transmissão. Expertize em técnicas de cultura celular, corte de tecidos e imunocitoquímica.
O LIMU (Laboratório de Imagiologia Microscópica e Ultramicroscópica) faz estudos de microscopia e imagiologia avançada de células e tecidos. Tem equipamento para realizar todos os procedimentos laboratoriais necessários à preparação de amostras para microscopia ótica e para microscopia eletrónica de transmissão. Expertize em técnicas de cultura celular, corte de tecidos e imunocitoquímica.
Laboratory of Support to Research in Molecular Medicine (LAIMM) -
Faculdade de Medicina da Universidade do Porto
The Laboratory of Support to Research in Molecular Medicine was created to promote the development of medical research. It offers logistical, operational and consulting services in the context of biomedical research projects, as well as custom molecular biology laboratory services, mutant and transgenic mouse models production, and scientific training.
The Laboratory of Support to Research in Molecular Medicine was created to promote the development of medical research. It offers logistical, operational and consulting services in the context of biomedical research projects, as well as custom molecular biology laboratory services, mutant and transgenic mouse models production, and scientific training.
Magnetic Resonance Imaging -
ICNAS - Institute for Nuclear Sciences Applied to Health
Service include a MRI machine available for clinical and research studies. Further details about the equipment for sensory stimulation can be found in the site.
Service include a MRI machine available for clinical and research studies. Further details about the equipment for sensory stimulation can be found in the site.
Mass Spectrometry -
iMed.ULisboa/ FFULisboa Research Institute for Medicines/ Faculdade de Farmácia, Universidade de Lisboa
The mass spectrometry laboratory was created in 2008 and is located at iMed.UL, Faculdade de Farmácia, Universidade de Lisboa. The equipment was financed by project REDE/1518/REM/2005 and is included in the group of equipment from the National Mass Spectrometry Network. This equipment consists of a liquid chromatograph and a mass spectrometer (a triple quadrupole) equipped with two ion sources (electrospray and atmospheric pressure chemical ionization), suitable for the identification and...
The mass spectrometry laboratory was created in 2008 and is located at iMed.UL, Faculdade de Farmácia, Universidade de Lisboa. The equipment was financed by project REDE/1518/REM/2005 and is included in the group of equipment from the National Mass Spectrometry Network. This equipment consists of a liquid chromatograph and a mass spectrometer (a triple quadrupole) equipped with two ion sources (electrospray and atmospheric pressure chemical ionization), suitable for the identification and...
Mass Spectrometry Unit -
Center for Neuroscience and Cell Biology
The Unit is specialized in the identification and quantification of proteins from complex samples, identification of post-translational modifications, and identification and quantification of metabolites. It is mainly focused on running R&D projects from both partners, as well as other collaborators (from CNC, Biocant, other R&D institutes and private companies).
The Unit is specialized in the identification and quantification of proteins from complex samples, identification of post-translational modifications, and identification and quantification of metabolites. It is mainly focused on running R&D projects from both partners, as well as other collaborators (from CNC, Biocant, other R&D institutes and private companies).
Medical Thermal Images (Thermography) -
INEGI - Institute of Science and Innovation in Mechanical and Industrial Engineering
This service centre provides thermal images of human body and animals as a complementary diagnosis method at clients’ site, by certified EAT (European Association of Thermology) association members.
This service centre provides thermal images of human body and animals as a complementary diagnosis method at clients’ site, by certified EAT (European Association of Thermology) association members.
Microscopy Shared Technical Facility (MicroSTF) -
Life and Health Science Research Institute (ICVS)
MicroSTF coordinates the microscopy equipment of the ICVS and offers confocal and laser microdissection services to industry and academia. The MicroSTF team is composed of a specialized lab technician and is equipped with several conventional light and fluorescence microscopes, plus confocal, laser microdissection and stereology microscopes.
MicroSTF coordinates the microscopy equipment of the ICVS and offers confocal and laser microdissection services to industry and academia. The MicroSTF team is composed of a specialized lab technician and is equipped with several conventional light and fluorescence microscopes, plus confocal, laser microdissection and stereology microscopes.
Microscopy Unit -
Center for Neuroscience and Cell Biology
The Microscopy Unit, at the Center for Neuroscience and Cell Biology (MICC-CNC), is a centralized facility where users receive the support required to carry out conventional and advanced imaging techniques, based on Light Microscopy. The unit has combined resources to provide state-of-the-art equipment that is open to all researchers. We offer the same services to academic investigators or companies.
The Microscopy Unit, at the Center for Neuroscience and Cell Biology (MICC-CNC), is a centralized facility where users receive the support required to carry out conventional and advanced imaging techniques, based on Light Microscopy. The unit has combined resources to provide state-of-the-art equipment that is open to all researchers. We offer the same services to academic investigators or companies.
Molecular Diagnostics -
Life and Health Science Research Institute (ICVS)
The Molecular Diagnostics unit at ICVS provides molecular diagnostics of genetic disorders, namely of a neurodevelopmental nature (intellectual disability, epilepsy) but also encompassing malformations. We perform genomewide analysis of Copy Number Variations using Array Comparative Genomic Hybridization (aCGH), also known as molecular karyotyping, as well as gene-specific sequence or dosage analysis. We offer analysis of specific genes but also develop novel assays on demand.
The Molecular Diagnostics unit at ICVS provides molecular diagnostics of genetic disorders, namely of a neurodevelopmental nature (intellectual disability, epilepsy) but also encompassing malformations. We perform genomewide analysis of Copy Number Variations using Array Comparative Genomic Hybridization (aCGH), also known as molecular karyotyping, as well as gene-specific sequence or dosage analysis. We offer analysis of specific genes but also develop novel assays on demand.
Natural Products Unit -
BIOALVO SA
BIOALVO owns a large natural extract library mainly derived from marine microorganisms. In order to avoid the hurdle of having found a great bioactive and then not being able to resupply in the necessary scale, BIOALVO has developed an internal natural extracts manufacturing unit. At BIOALVO we can go from mg produced in a Labscale supply to Pilot scale Supply and even to Large scale supply, in the orders of several kg, guarantying a well controlled and smooth manufacturing process.
BIOALVO owns a large natural extract library mainly derived from marine microorganisms. In order to avoid the hurdle of having found a great bioactive and then not being able to resupply in the necessary scale, BIOALVO has developed an internal natural extracts manufacturing unit. At BIOALVO we can go from mg produced in a Labscale supply to Pilot scale Supply and even to Large scale supply, in the orders of several kg, guarantying a well controlled and smooth manufacturing process.
Natural Radioactivity -
Laboratory of Natural Radioactivity, Department of Earth Sciences, Faculty of Sciences and Technology, University of Coimbra
Scientific development and transfer of knowledge regarding sustainable practices to preserve environmental health, in the scientific domains of Medical Geology - Natural Radioactivity - indoor and soil radon gas concentrations, testing for radioactive parameters in waters, assessing radon gas retention ability as well as other radiological parameters in building materials, both natural and man-made; assessing the proportion of the bio(logical) component in fuel; carbon-14 dating.
Scientific development and transfer of knowledge regarding sustainable practices to preserve environmental health, in the scientific domains of Medical Geology - Natural Radioactivity - indoor and soil radon gas concentrations, testing for radioactive parameters in waters, assessing radon gas retention ability as well as other radiological parameters in building materials, both natural and man-made; assessing the proportion of the bio(logical) component in fuel; carbon-14 dating.
Neuroengineering and Advanced Human Sensing Laboratory -
INESC TEC
The main goal of the NeuroEngineering lab is to perform high-level interdisciplinary R&D in engineering and computational approaches applied to basic and clinical neuroscience, namely crossing several areas, such as Physics; Engineering (Electronics; Computation; etc.); Neurology; Neurosurgery; Neurophysiology; Neuroradiology and Neurobiology.
The main goal of the NeuroEngineering lab is to perform high-level interdisciplinary R&D in engineering and computational approaches applied to basic and clinical neuroscience, namely crossing several areas, such as Physics; Engineering (Electronics; Computation; etc.); Neurology; Neurosurgery; Neurophysiology; Neuroradiology and Neurobiology.
Neurophysiology Laboratory -
ICNAS - Institute for Nuclear Sciences Applied to Health
ICNAS host a main Neurophysiology laboratory including EEG, EMG, TMS, Eyetracking and other physiologic measures. These are often used as a multimodal experiment setup.
ICNAS host a main Neurophysiology laboratory including EEG, EMG, TMS, Eyetracking and other physiologic measures. These are often used as a multimodal experiment setup.
NMR LABORATORY -
Faculty of Health Sciences, University of Beira Interior
The installation of NMR laboratory (82 m2) was completed in May of 2011 and has two spectrometers; one operating at 1H frequency of 400 MHz and the other at 600 MHz equipped with QCI CryoProbe, enables detection of 13C, 31P and 15N. The other probes available are BBFO+, TXI inverse and HR MAS. These spectrometers are ideally for study proteomics, genomics, structure and drug design. Also a SampleJet installed on 600 MHz is equipped with 500 positions allows us to performed metabolomics studies.
The installation of NMR laboratory (82 m2) was completed in May of 2011 and has two spectrometers; one operating at 1H frequency of 400 MHz and the other at 600 MHz equipped with QCI CryoProbe, enables detection of 13C, 31P and 15N. The other probes available are BBFO+, TXI inverse and HR MAS. These spectrometers are ideally for study proteomics, genomics, structure and drug design. Also a SampleJet installed on 600 MHz is equipped with 500 positions allows us to performed metabolomics studies.
Nuclear Magnetic Resonance -
iMed.ULisboa/ FFULisboa Research Institute for Medicines/ Faculdade de Farmácia, Universidade de Lisboa
The NMR facility is equipped with a NMR Spectrometer (Bruker Avance 400). It promotes the use of nuclear magnetic resonance spectroscopy in the areas of structure-based drug design, including structure characterization, fragment-based drug design, metabolomics and dynamic host-guest interactions. These activities are part of our strategic interests in thematic areas of drug discovery, drug design and drug development.
The NMR facility is equipped with a NMR Spectrometer (Bruker Avance 400). It promotes the use of nuclear magnetic resonance spectroscopy in the areas of structure-based drug design, including structure characterization, fragment-based drug design, metabolomics and dynamic host-guest interactions. These activities are part of our strategic interests in thematic areas of drug discovery, drug design and drug development.
Núcleo de Prestação de Serviços (Clinical Analyses Core Laboratory), Faculdade de Farmácia, Universidade de Lisboa -
iMed.ULisboa/ FFULisboa Research Institute for Medicines/ Faculdade de Farmácia, Universidade de Lisboa
This service expresses the constant concern of Faculdade de Farmácia, Universidade de Lisboa with translational application of scientific research produced in iMed.UL, contributing to the improvement of the well-being of the population it serves. It provides specific and unique services related with clinical diagnostic and monitoring in the areas of clinical biochemistry and microbiology.
This service expresses the constant concern of Faculdade de Farmácia, Universidade de Lisboa with translational application of scientific research produced in iMed.UL, contributing to the improvement of the well-being of the population it serves. It provides specific and unique services related with clinical diagnostic and monitoring in the areas of clinical biochemistry and microbiology.
Pharmacovigilance -
Eurotrials, Consultores Científicos, S.A.
Pharmacovigilance plays an essential role in the protection of public health, especially in assessing the risks and benefits of medicinal products. The department works in continuous cooperation with its partners, whether they are small businesses or multinational companies.
Pharmacovigilance plays an essential role in the protection of public health, especially in assessing the risks and benefits of medicinal products. The department works in continuous cooperation with its partners, whether they are small businesses or multinational companies.
Preclinical services -
BnML - Behavioral and Molecular Lab
Bn’ML provides customized preclinical behavioral and molecular analysis services using rodent animal models, for testing the potential of new therapeutic solutions. Bn´ML services include: -flexible design of the study, according to customer’s requirements -induction of the disease model -administration of the compound -evaluation of the therapeutic potential -preparation of a final report with interpretative analysis of the results and study conclusions
Bn’ML provides customized preclinical behavioral and molecular analysis services using rodent animal models, for testing the potential of new therapeutic solutions. Bn´ML services include: -flexible design of the study, according to customer’s requirements -induction of the disease model -administration of the compound -evaluation of the therapeutic potential -preparation of a final report with interpretative analysis of the results and study conclusions
Protein Production and Purification Unit -
IBMC - Institute for Molecular and Cell Biology
The Protein Production and Purification Unit (UP3) provides access to state-of-the-art equipment for the expression, purification and biochemical/biophysical analysis of recombinant proteins. This facility provides both scientific and technical expertise, actively participating in the establishment of interdisciplinary research and networking activities involving internal and external research groups.
The Protein Production and Purification Unit (UP3) provides access to state-of-the-art equipment for the expression, purification and biochemical/biophysical analysis of recombinant proteins. This facility provides both scientific and technical expertise, actively participating in the establishment of interdisciplinary research and networking activities involving internal and external research groups.
Proteomics and Mass Spectrometry -
IPATIMUP
IPATIMUP Proteomics Unit provides access to the analysis of different kind of molecules by MALDI mass spectrometry. The Unit is specially focused in the analysis of protein samples from solutions, bands or protein spots from 1D or 2D electrophoresis gels.
IPATIMUP Proteomics Unit provides access to the analysis of different kind of molecules by MALDI mass spectrometry. The Unit is specially focused in the analysis of protein samples from solutions, bands or protein spots from 1D or 2D electrophoresis gels.
Quality -
Eurotrials, Consultores Científicos, S.A.
The Quality department is an independent department made up of a multidisciplinary group of auditors. They have vast experience in quality control and quality assurance, namely GCP audits. In addition to outsourcing, they ensure that the work of the other Eurotrials departments complies with ISO 9001:2008, the legislation in different countries, the rules of good clinical practice (ICH-GCP and GCP Directive) and any other applicable regulations.
The Quality department is an independent department made up of a multidisciplinary group of auditors. They have vast experience in quality control and quality assurance, namely GCP audits. In addition to outsourcing, they ensure that the work of the other Eurotrials departments complies with ISO 9001:2008, the legislation in different countries, the rules of good clinical practice (ICH-GCP and GCP Directive) and any other applicable regulations.
Radioactivity -
IBMC - Institute for Molecular and Cell Biology
Management of the Radioactivity Facilities: improve the safety of workers handling radioactivity, maintain a safe disposal of radioactive wastes and provide mensal dosimetry. Everyone starting to work with radioactivity must undergo a Radiation Safety training session and require a dosimeter. All rooms and Gammacell Irradiator have a valid license given by DGS.
Management of the Radioactivity Facilities: improve the safety of workers handling radioactivity, maintain a safe disposal of radioactive wastes and provide mensal dosimetry. Everyone starting to work with radioactivity must undergo a Radiation Safety training session and require a dosimeter. All rooms and Gammacell Irradiator have a valid license given by DGS.
Radioisotope Unit -
iMed.ULisboa/ FFULisboa Research Institute for Medicines/ Faculdade de Farmácia, Universidade de Lisboa
The Radioisotope Unit (gamma and beta emission) at Faculdade de Farmácia, Universidade de Lisboa (FFUL) is located in Edifício F, Campus Lumiar. The radioactivity facility is an infrastructure built specifically for this purpose and is essential for research and development activities in iMed.UL, including research in partnership with industry.
The Radioisotope Unit (gamma and beta emission) at Faculdade de Farmácia, Universidade de Lisboa (FFUL) is located in Edifício F, Campus Lumiar. The radioactivity facility is an infrastructure built specifically for this purpose and is essential for research and development activities in iMed.UL, including research in partnership with industry.
Regulatory Affairs -
Inovapotek, Lda
Cosmetic products must obey to strict legislation wherever they are marketed. In the European Union a common Regulation is applicable to all member states, together with several Amendments, as well as other international guidelines that may not be mandatory, but are nevertheless useful for the cosmetic industry. To help its clients keep up with the European Regulation inovapotek provides a full range of regulatory affairs services.
Cosmetic products must obey to strict legislation wherever they are marketed. In the European Union a common Regulation is applicable to all member states, together with several Amendments, as well as other international guidelines that may not be mandatory, but are nevertheless useful for the cosmetic industry. To help its clients keep up with the European Regulation inovapotek provides a full range of regulatory affairs services.
Regulatory Strategy & Affairs -
Eurotrials, Consultores Científicos, S.A.
This department is responsible for the whole process of registering medicines, medical devices, cosmetics and nutritional products. It monitors their life cycle and provides strategic advice and consultancy on regulatory processes.
This department is responsible for the whole process of registering medicines, medical devices, cosmetics and nutritional products. It monitors their life cycle and provides strategic advice and consultancy on regulatory processes.
Research & Development -
Eurotrials, Consultores Científicos, S.A.
Eurotrials has all the competences and experience needed to operate in the development of drugs, biodrugs and medical devices and can analyse projects (ideas and products) and draft plans for strategic and regulatory development. Eurotrials works with different partners in the RTD process: • Biotechnology companies • Pharmaceutical industry • Research groups –institutes, academia, hospitals • Financial groups • Consultancy firms
Eurotrials has all the competences and experience needed to operate in the development of drugs, biodrugs and medical devices and can analyse projects (ideas and products) and draft plans for strategic and regulatory development. Eurotrials works with different partners in the RTD process: • Biotechnology companies • Pharmaceutical industry • Research groups –institutes, academia, hospitals • Financial groups • Consultancy firms
RESEARCH & DEVELOPMENT -
Clinical Academic Center – Braga, Association (CCAB)
The Clinical Academic Center - Braga, Association (CCAB) is in a unique and privileged position to ally research with clinical aspects, maximizing the development of innovative biomaterials, diagnostic strategies, regenerative approaches and therapeutic products. The CCAB offers a full-range of clinical research services, with a wide spectrum of infrastructures and with full technical support.
The Clinical Academic Center - Braga, Association (CCAB) is in a unique and privileged position to ally research with clinical aspects, maximizing the development of innovative biomaterials, diagnostic strategies, regenerative approaches and therapeutic products. The CCAB offers a full-range of clinical research services, with a wide spectrum of infrastructures and with full technical support.
Robotics Unit -
BIOALVO SA
This is BIOALVO’s robotized facility that provides the services of a liquid handling system with a tip head adaptable to 8, 96 or 384-tip adaptors, an incubator for 44 microplates and a microplate reader. These equipments can be used separately or together as a modular system, with numerous applications such as library replication/dilution, enzymatic, fluorescence or other in vitro assays, or large scale screenings, enabling the processing of a large number of samples in a fast, effective way.
This is BIOALVO’s robotized facility that provides the services of a liquid handling system with a tip head adaptable to 8, 96 or 384-tip adaptors, an incubator for 44 microplates and a microplate reader. These equipments can be used separately or together as a modular system, with numerous applications such as library replication/dilution, enzymatic, fluorescence or other in vitro assays, or large scale screenings, enabling the processing of a large number of samples in a fast, effective way.
Rodon Biologics -
Rodon Biologics
Rodon Biologics is a service provider company with more than 15 years experience in protein recombinant production andprocess development. Rodon is a spin-off of Biotecnol, a company operating in Portugal since 1996 dedicated to biological development. Rodon services include: protein production, analytical characterization, cell-based assays, cell line and process development. Rodon is customer-centric and guarantees that the projects are executed under a quality system.
Rodon Biologics is a service provider company with more than 15 years experience in protein recombinant production andprocess development. Rodon is a spin-off of Biotecnol, a company operating in Portugal since 1996 dedicated to biological development. Rodon services include: protein production, analytical characterization, cell-based assays, cell line and process development. Rodon is customer-centric and guarantees that the projects are executed under a quality system.
Safety and Efficacy Studies -
Inovapotek, Lda
Cosmetics including toiletries, skin care and sunscreen products can cause adverse skin reactions. Each new raw material, active ingredient and cosmetic product should be submitted to thorough safety assessment. Also, claims substantiation is crucial, not only to fulfil with regulatory requirements, but also to enhance the value of a given cosmetic product or ingredient. Inovapotek offers a wide range of standard and customized tests of safety and efficacy.
Cosmetics including toiletries, skin care and sunscreen products can cause adverse skin reactions. Each new raw material, active ingredient and cosmetic product should be submitted to thorough safety assessment. Also, claims substantiation is crucial, not only to fulfil with regulatory requirements, but also to enhance the value of a given cosmetic product or ingredient. Inovapotek offers a wide range of standard and customized tests of safety and efficacy.
Sensing Future Technologies -
Sensing Future Technologies
The company designs, develops and implements medical devices with a high degree of innovation, functionality and applicability. Sensing Future Technologies is mainly dedicated to 5 main areas: 1. Stabilometry & Baropodometry: Balance/Pressure 2. Robotics, Haptic Devices and Telemedicine 3. Monitoring for Homes and Hospitals (Healthcare IoT) 4. Virtual Reality in Vestibular Rehabilitation 5. Fall Risk for elderly people The company has brought to market various commercial healthcare products!
The company designs, develops and implements medical devices with a high degree of innovation, functionality and applicability. Sensing Future Technologies is mainly dedicated to 5 main areas: 1. Stabilometry & Baropodometry: Balance/Pressure 2. Robotics, Haptic Devices and Telemedicine 3. Monitoring for Homes and Hospitals (Healthcare IoT) 4. Virtual Reality in Vestibular Rehabilitation 5. Fall Risk for elderly people The company has brought to market various commercial healthcare products!
Sequencing Service -
IPATIMUP
The sequencing service serves investigators and technicians who develop their work at IPATIMUP. This service is accountable for maintaining and handling the automated sequencers present at IPATIMUP facilities. This service includes the automated analysis of PCR and sequencing products (GeneMapper and Sequencing Analysis, respectively), by organizing the samples delivered on each day and distributing them through the appropriate instrument. It also performs sequencing reactions and its analysis.
The sequencing service serves investigators and technicians who develop their work at IPATIMUP. This service is accountable for maintaining and handling the automated sequencers present at IPATIMUP facilities. This service includes the automated analysis of PCR and sequencing products (GeneMapper and Sequencing Analysis, respectively), by organizing the samples delivered on each day and distributing them through the appropriate instrument. It also performs sequencing reactions and its analysis.
Serviço de Cirurgia Experimental -
Faculdade de Medicina da Universidade do Porto
Excelentes condições de trabalho para cirurgia animal e para investigação. Destaca-se por ter sido aqui pela primeira vez a nível mundial que se obtiveram imagens radiográficas de vasos linfáticos e se efectuou um transplante cardíaco experimental. Mais recentemente efetuaram-se transplantes hepáticos em porcos, bem como diversos trabalhos com biomateriais dos quais resultaram inúmeras publicações e teses de Doutoramento bem como vários cursos internacionais (trauma, cirurgia laparoscópica).
Excelentes condições de trabalho para cirurgia animal e para investigação. Destaca-se por ter sido aqui pela primeira vez a nível mundial que se obtiveram imagens radiográficas de vasos linfáticos e se efectuou um transplante cardíaco experimental. Mais recentemente efetuaram-se transplantes hepáticos em porcos, bem como diversos trabalhos com biomateriais dos quais resultaram inúmeras publicações e teses de Doutoramento bem como vários cursos internacionais (trauma, cirurgia laparoscópica).
SITI - Informatics Systems and Technologies -
COPELABS - Cognitive and People-centric Computing unit
SITI is an R&D group of COPELABS with a vision where nomadic people become the centre of the networking system. Users on the move are part of communities and will not only be consumers of information but also active providers of different Internet services, such as coordination of connectivity to different access networks. SITI dedicates its R&D effort to the development of new technological solutions in the fields of pervasive wireless systems and social mobile networking dynamics.
SITI is an R&D group of COPELABS with a vision where nomadic people become the centre of the networking system. Users on the move are part of communities and will not only be consumers of information but also active providers of different Internet services, such as coordination of connectivity to different access networks. SITI dedicates its R&D effort to the development of new technological solutions in the fields of pervasive wireless systems and social mobile networking dynamics.
Slides Digitalization Unit -
IPATIMUP
The Slides Digitalization Unit (UDL) aims to convert histological and cytological glass slides into high-quality and high-resolution digital slides. The UDL provides as well the chance to storage those images in an appropriate server.
The Slides Digitalization Unit (UDL) aims to convert histological and cytological glass slides into high-quality and high-resolution digital slides. The UDL provides as well the chance to storage those images in an appropriate server.
Solid State Characterization -
Hovione FarmaCiencia SA
Solid state chemistry in its broadest manifestation involves using the crystal structure and solid state analytical information to explain solid-state properties, which is crucial to develop new drugs. At Hovione, the mission of the group is to collaborate with customers in the field of solid state, particularly in the characterization of solid phases of raw materials to finished products, from API to drug products in all stages of development and production. Innovation is continuously promoted.
Solid state chemistry in its broadest manifestation involves using the crystal structure and solid state analytical information to explain solid-state properties, which is crucial to develop new drugs. At Hovione, the mission of the group is to collaborate with customers in the field of solid state, particularly in the characterization of solid phases of raw materials to finished products, from API to drug products in all stages of development and production. Innovation is continuously promoted.
STATISTICS -
Clinical Academic Center – Braga, Association (CCAB)
The CCAB statistic team provides a wide range of services adapted to the needs of each project, such so statistical analyses, study reports and assistance in preparing articles for scientific journals.
The CCAB statistic team provides a wide range of services adapted to the needs of each project, such so statistical analyses, study reports and assistance in preparing articles for scientific journals.
Stem Cell Bioengineering and Regenerative Medicine Laboratory -
Institute for Biotechnology and Bioengineering at Instituto Superior Técnico
R&D activities at the Stem Cell Bioengineering and Regenerative Medicine Laboratory (Tagus Park IST Campus) are focused on the development of bioprocesses to cultivate and purify stem cells and their derivatives at a manufacturing scale. Both human adult and pluripotent (embryonic and reprogrammed cells) stem cells are used as models systems specially targeting their application in Regenerative Medicine settings and toxicology/pharmacological testing, respectively.
R&D activities at the Stem Cell Bioengineering and Regenerative Medicine Laboratory (Tagus Park IST Campus) are focused on the development of bioprocesses to cultivate and purify stem cells and their derivatives at a manufacturing scale. Both human adult and pluripotent (embryonic and reprogrammed cells) stem cells are used as models systems specially targeting their application in Regenerative Medicine settings and toxicology/pharmacological testing, respectively.
Teaching and Training -
Eurotrials, Consultores Científicos, S.A.
Eurotrials develops training programs based upon the knowledge that has been accumulated by the several areas of the company. The training areas are developed with a strong practical component and interactivity under the format of: Training Courses | Modules for post graduations or masters | Workshops | Seminaries included in congresses or meetings | Individual trainings. We develop courses tailored to your needs!
Eurotrials develops training programs based upon the knowledge that has been accumulated by the several areas of the company. The training areas are developed with a strong practical component and interactivity under the format of: Training Courses | Modules for post graduations or masters | Workshops | Seminaries included in congresses or meetings | Individual trainings. We develop courses tailored to your needs!
