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Foie Gras | Bioenergetic Remodeling in the Pathophysiology and Treatment of Non-Alcoholic Fatty Liver Disease

Center for Neuroscience and Cell Biology
Project classification

Scientific area

3.1 Basic medicine

Discipline(s)

Physiology (including cytology)

Project description

Project title

Foie Gras | Bioenergetic Remodeling in the Pathophysiology and Treatment of Non-Alcoholic Fatty Liver Disease

Scientific Coordinator's name:

Paulo Oliveira

Scientific Coordinator's e-mail:

pauloliv@ci.uc.pt

Principal R&D Unit:

Center for Neuroscience and Cell Biology

Other R&D Units involved in the project:

BIOCANT

Project keyword(s)

Fatty liver disease, metabolism, gut, liver, mitochondria, biomarkers, science awareness, communication.

Short abstract and comments

In Western Societies, there has been a recent surge of non-alcoholic fatty liver disease (NAFLD). Its progression to nonalcoholic steatohepatitis (NASH) is a leading risk factor for development of Type 2 diabetes, cirrhosis, and hepatocellular carcinoma. FOIE GRAS is first in supporting a cohesive and synergistic intersection of complementary and interdisciplinary training skills from academic and non-academic partners. FOIE GRAS combines strong scientific expertise with integrated and complementary training in translational research, clinical practice, technology commercialization, and public outreach, the combination of which in targeting NAFLD is lacking in the EU. Industrial partners Mediagnost and Micro-biolytics provide experience on technology commercialization alongside scientific contributions while the affiliated patient organization will contribute with important training in societal awareness topics.

Potential uses/indications

ESRs training will utilize network-wide workshops and secondments to foster translation of basic research to clinical applications and SME creation. This diverse yet integrated skill set enhances the employment prospects of the trained researchers in both academic and non-academic sectors. Researchers will be endowed with excellent basic scientific knowledge and timely technology transfer know-how for developing novel therapeutic approaches for reversing the burden of NAFLD, thereby advancing both health and economic well-being of European citizens and approaching NAFLD research in the EU from its counterparts in the US and Asia.

Status

Ongoing

Partner Status: Seeking Partners?

No

Grant number (QREN, FP7, Eureka, etc)

H2020-MSCA-ITN-2016- 722619

Last edited on

2017-03-30 10:57:56

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