Scientific area
1.4 Chemical sciences
Discipline(s)
Physical chemistry, Polymer science, Electrochemistry (dry cells, batteries, fuel cells, corrosion metals, electrolysis)
Colloid chemistry
Analytical chemistry
Project title
Biomimetic/nanobioconjugates flexible platforms for sensitive immunosensing
Scientific Coordinator's name:
Ana Pimenta da Gama da Silveira Viana
Scientific Coordinator's e-mail:
anaviana@fc.ul.pt
Principal R&D Unit:
Centro de Química e Bioquímica (CQB)
Other R&D Units involved in the project:
Institute of Mechanics, Chinese Academy of Sciences (IMECH)
Project keyword(s)
Surface bio-functionalization; immunosensors; semiconducting nanoparticles; optical and electrochemical detection
Short abstract and comments
The major scientific goal of this project is to develop simple and disruptive surface chemistry to push forward the field of biosensing, severely limited by the short shelf-life, reproducibility and portability of the currently used strategies. Regarding the immunosensors development, two main aspects will be optimized: i) the immobilization of a primary antibody on a phospholipid based biomimetic surface; and ii) the signal amplification methodology to detect the target antigen by a secondary antibody. It is expected to develop innovative yet simple approaches to enhance the detection (electrochemical or optical) of these biological events
Potential uses/indications
Development of simple and innovative methodologies to be employed in the building of high sensitive immunosensor platforms to detect any antibody/antigen of interest. Construction of a pre-industrial prototype of a biosensing equipment to detect toxins (e.g OTA or AFLO) with high sensitivity.
Status
Ongoing
Partner Status: Seeking Partners?
No
Grant number (QREN, FP7, Eureka, etc)
PTDC/CTMNAN/0994/2014
Last edited on
2016-11-21 18:03:50