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Human Health: Molecular Interventions and Regulation Mechanisms.

Faculdade de Ciências da Universidade de Lisboa
Project classification

Scientific area

1.4 Chemical sciences

Discipline(s)

Physical chemistry, Polymer science, Electrochemistry (dry cells, batteries, fuel cells, corrosion metals, electrolysis)
Organic chemistry
Analytical chemistry

Project description

Project title

Human Health: Molecular Interventions and Regulation Mechanisms.

Scientific Coordinator's name:

Rodrigo F. M. de Almeida

Scientific Coordinator's e-mail:

rodrigo.almeida@fc.ul.pt

Principal R&D Unit:

Centro de Química e Bioquímica (CQB)

Other R&D Units involved in the project:

Other R&D units involved in the project

Project keyword(s)

phytochemicals, biophysical methods, medicinal chemistry, biological chemistry

Short abstract and comments

Phytochemicals are known to exert several health benefits namely through antioxidant activity. A mechanism for the action of phytochemicals may be found at the level of the cell membranes. In order to gain a detailed understanding about phytochemicals action and be able to model the ability of a given phytochemical compound to fine tune cell protection mechanisms, the following aspects are being studied: (i) interaction of phytochemical compounds with lipid membranes; (ii) phytochemicals permeation through the lipid membranes; (iii) interaction of phytochemicals with specific membrane lipids and proteins; (iv) general effects of phytochemicals on human cells.

Potential uses/indications

we intend to fully explore the application of phytochemicals in the prevention/treatment of multifactorial and age-related diseases

Status

Ongoing

Partner Status: Seeking Partners?

Yes

Grant number (QREN, FP7, Eureka, etc)

UID/MULTI/00612/2013

Last edited on

2016-11-23 17:45:28

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