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Application of combined bioinformatic and experimental approaches to elucidate a clinical preeclamsia management strategy

IBMC - Institute for Molecular and Cell Biology
Project classification

Scientific area

1.6 Biological sciences (Medical sciences go to scientific area 3.n; Agricultural sciences go to scientific area 4.n)

Discipline(s)

Reproductive biology (medical aspects go to scientific area 3.n)

Project description

Project title

Application of combined bioinformatic and experimental approaches to elucidate a clinical preeclamsia management strategy

Scientific Coordinator's name:

Irene Rebelo

Scientific Coordinator's e-mail:

irebelo@ff.up.pt

Principal R&D Unit:

Biology of Inflammation and Reproduction

Other R&D Units involved in the project:

Other R&D units involved in the project

Project keyword(s)

Preeclampsia, bioinformatics, pregnancy hypertension

Short abstract and comments

Even when preeclampsia mechanism is unknown, the number of studies about different treatment or prevention alternative is actually increasing, however, without success in the preeclampsia management. On the other hand, these efforts combined with basic investigations, have being increasing our knowledge about the genes and proteins involved during the preeclampsia manifestation. A proper analysis and evaluation of this available information could be the key not only for the preclampsia puzzle understanding but also to study and explore therapeutic or preventive approaches. The goals of the present project are, through combined approaches of bioinformatic and experimental testing, to explore therapeutic or preventive alternative for preeclamptic pregnant women management as well as to evaluate the future pathologic risk of women with previous history of preeclampsia.

Potential uses/indications

Early preeclampsia diagnosis and/or intervention.

Status

Ongoing

Partner Status: Seeking Partners?

Yes

Grant number (QREN, FP7, Eureka, etc)

SFRH/BPD/72391/2010

Last edited on

2013-02-07 11:36:05

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